Will killing a Little Sister change the game's ending?

I accidentally harvested a Little Sister, but it had been so long since my last save that I didn’t want to reload, and just kept playing. Now I’ve found out that apparently the game’s ending changes depending on whether you harvest or rescue the Little Sisters. Will one accidental kill ruin my chances at the “good” ending?

I tried to Google this, and the various answers out there are about 50/50 “Even a single kill will change the ending” or “You have to kill at least two or three before anything changes.” Because of that, I’d appreciate some kind of source for the answer if possible.

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  • 4 Solutions collect form web for “Will killing a Little Sister change the game's ending?”

    You should be OK, as long as you avoid harvesting any more little sisters.

    From the IGN Game Guide (my emphasis added):

    There are two possible endings for BioShock that depend on how you
    treated little sisters throughout the game. If you choose to “harvest”
    more than one little sister, you will get the bad BioShock ending. If,
    however, you “harvest” no more than one little sister but “rescue” the
    others, you will get the good BioShock ending.

    However, there are two bad endings, depending upon how bad you have been. Various YouTube videos show them all.

    If you save all the little sister you get the good ending (even if you kill one LS) but if you decide to harvest more then one or all you will get the alternative endings. There are two and each one depends if you saved some and harvested some or just decided to harvest all. Though the two negative endings are similar the ‘feeling’ from the narrator changes not the story. You release mayham upon the real world if you decide to be a killer of LS. sorry for the spoiler… NOT

    I think my game glitched. I harvested two and at the end I was accused of harvesting all of them. It wasn’t fair.

    I have just completed the game with the good ending. I think I killed the second little sister, the first one the doctor asks you to save, but the second Atlas says “would you kindly kill the little monster.” Don’t want to spoil, but I guess that kind of makes it okay. If you get to Ryan you will understand.

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