Can things be unlocked in seeded runs?

I noticed after getting a seed from my friend, ands beating the boss rush (for the first time with cain) I didn’t unlock anything. Also I had a seeded run to get Guppy, but that also didn’t unlock anything. Do seeded runs count towards anything? Do donation machines show up on seeded runs, and if so, do donations made on seeded runs count?

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  • Can the D4 or D100 give me Godhead?
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  • How do I unlock the hidden character “The Lost”?
  • What does the donation machine do?
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  • How do I rebind the controls in BoI: Rebirth?
  • 3 Solutions collect form web for “Can things be unlocked in seeded runs?”

    If you enter a seed, you will not be able to earn achievements or unlock items during that run. There is also no donation machine in the shop (but shop upgrades from previous runs still make more items available).

    This is shown by the no achievement icon:
    http://i.imgur.com/pnb9CYz.png

    Nope, seeded runs don’t unlock anything. They also do not have a donation machine available, so you can’t donate (or steal money from the donation machine by blowing it up).

    There is a exploit where you can unlock things on a seeded runs. I’m not sure if it still works, but here’s the process:

    1. Put in seed
    2. Exit back to where you have to select a game save
    3. Pick a Character and voila! A seeded run and you can unlock things.
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